The Effect of Imbalance in the “Filtrate Fraction” of the Vitamin B Complex in Dogs

By Dr. Agnes Fay Morgan

Summary: “The problem with synthetic vitamins is they’re pure,” said the great holistic nutritionist Dr. Royal Lee. What he meant is that, whereas vitamins in food are naturally accompanied by countless cofactors critical for the proper function of the nutrient, synthetic vitamins are lone chemicals, devoid of their required, synergistic helpers. The difference between the two, Dr. Lee said, is the difference between a nutritive and a pharmacological effect. And many early nutrition studies support this idea. In the experiment presented here, eminent nutrition scientist Dr. Agnes Fay Morgan discusses the surprising effects of “enriching” the feed of dogs on a low-vitamin-B diet with synthetic supplements. Whereas dogs with no supplementation developed the symptoms expected of a partial lack of vitamin B—fatigue, poor digestion, slowed growth—the dogs given synthetic B vitamins developed different and far more grave conditions, including progressive neuromuscular degeneration followed by paralysis and, finally, death. These “unexpected failures of nutrition” were exactly the type of pharmacological effects Dr. Lee decried regarding synthetic vitamins, and they compelled Dr. Morgan to warn of the “possible danger of the administration of large amounts” of artificial B vitamins, adding that “fortification of foods with those vitamins” could precipitate conditions worse than those created by a deficiency. This did not deter the Food and Drug Administration, however, which less than two years after this study launched its flour “enrichment” program, requiring the addition of various synthetic B vitamins to all white bread in America—some of those chemicals the very compounds that hurried Dr. Morgan’s dogs to an unnatural death. From Science, 1941.

The Vitamins in Medicine, Part 1 (Vitamin A and the B Complex)

By Franklin Bicknell, MD, and Frederick Prescott, MD

Summary: Nutrition and medicine have seldom seen eye to eye. Though the discovery of the vitamins in the early twentieth century did cause some physicians to grasp the profound connection between vitamin deficiencies and degenerative disease, medicine as an institution never truly embraced this idea. Ultimately, the American Medical Association declared—in concert with the industrial food industry and the U.S. Food and Drug Administration—that most Americans do not suffer vitamin deficiencies of any consequence. This position, however, contradicts decades of scientific study, as famed natural nutritionist Dr. Royal Lee argued throughout his career. One of the books Dr. Lee cited most often in making his case was the text here, The Vitamins in Medicine, by British physicians Drs. Franklin Bicknell and Frederick Prescott. Backed by over 4500 scientific references, the text sums the totality of scientific knowledge about the vitamins at the time of its publication in the mid-twentieth century. While the book does take some typically medical views of vitamins, e.g., that they are single chemical substances and not synergistic biochemical complexes, as Dr. Lee taught, it nevertheless supports strongly the notion that many, if not most, of our modern ailments stem from partial (or “subclinical”) vitamin deficiencies. “This book not only tells of the ravages caused by ignoring nature’s ways,” Dr. Lee said, “but it also shows us the way to prevent these bodily damages.” In the first part of the text (see link to PDF below), the authors discuss vitamin A as well as the various B vitamins. In Part 2, Bicknell and Franklin go on to address vitamins C, D, E, and K and a host of other vital nutrients. Though the information in this book is over seven decades old, it is still incredibly valuable today, when so few health practitioners actually know what the vitamins do—or what a lack of them can cause. Lee Foundation for Nutritional Research, 1953. Original publisher William Heinemann, London.

Honey in Nutrition

By William Miller

Summary: An excellent overview of the value of raw honey. Author William Miller compares the nutritional qualities of this extraordinary food, manufactured by bees for millions of years, to those of refined sugar. His conclusion? They’re complete opposites nutritionally, with honey providing vitamins, minerals, and other factors critical for life and white sugar providing nothing more than empty calories. Lee Foundation for Nutritional Research reprint 119, 1955. Original source unknown.

Maternal Malnutrition and Fetal Prenatal Developmental Malformation

By Howard H. Hillemann, PhD

Summary: A thoroughly researched report on the birth and developmental defects known to result from specific nutrient deficiencies in human and test-animal mothers during pregnancy. Professor Dr. Howard Hillemann of Oregon State College covers deficiencies of vitamins A, C, and E, fats, carbohydrates, the B complex vitamers (including folate), protein, calcium, phosphorous, and manganese. Includes 61 references. Published by the Lee Foundation for Nutritional Research, reprint 66A, 1956.

Maternal Malnutrition and Congenital Deformity

By Howard H. Hillemann, PhD

Summary: In this lecture from 1958, Oregon State professor Dr. Howard Hillemann breaks down the number of birth defects occurring in the United States by cause, noting in particular the increasing numbers of defects attributable to environmental chemicals, food additives, and prenatal malnutrition. The report includes a comprehensive discussion of the role of vitamins and minerals in prenatal nutrition, addressing each nutrient individually. Published by the Lee Foundation for Nutritional Research, reprint 66B, 1958.

The National Malnutrition

By D.T. Quigley, MD

Summary: Daniel Quigley was a physician at the Nebraska College of Medicine who rose to prominence with the 1929 publication of his book The Conquest of Cancer. Like many doctors of the time, his clinical experience led him to believe that malnutrition—due to the replacement of natural foods with industrial ones—was not only more widespread in America than the medical establishment believed, but that vitamin and mineral deficiencies, more than anything else, were responsible for the exploding rates of degenerative illness throughout the country and world. In 1943, after years of observing the successful application of whole food nutritional therapy in his practice, Dr. Quigley published the following textbook through the Lee Foundation for Nutritional Research. In it he warns Americans to avoid completely white flour, white sugar, and corn syrup, each of the refined products fostering disease by delivering calories but precious few of the micronutrients needed by the body for proper function and fighting infection. For optimal nutrition Dr. Quigley recommends a diet of raw milk, eggs, whole grains, seafood, organ meats, fresh vegetables, yeast, and butter—a prescription of highly nutrient dense foods that makes just as much sense today as it did then, when these substances were known to nutritionists simply as “the protective foods.” Published by the Lee Foundation for Nutritional Research, 1943.

Natural Versus Synthetic or Crystalline Vitamins

By Dr. Royal Lee

Summary: In this brief article, Dr. Royal Lee presents his classic metaphor of holistic nutrition likening a true vitamin to a watch. Just as a watch consists of numerous pieces that all work together to perform a function (telling time), a true vitamin is a complex of countless synergistic factors that work together to perform the function of delivering a nutritive effect to the body. And just as separating a few pieces from a watch and expecting them to tell time is absurd, isolating (or synthesizing) a single component of a natural vitamin and expecting it to nourish the body is folly. Vitamin Products Company, 1952.